Youth clubs have been implemented at two clinics (a youth-specific clinic and a general clinic) in the Khayelitsha area of Cape Town by MSF in partnership with local health authorities. In addition, the model has been endorsed in the South African national adherence policy. Youth clubs are closed groups of approximately 20 members, including youth who are ART ineligible, newly initiated and stable on ART. Separate groups are formed for youth still attending school and older youth. Youth clubs are led by lay health care workers and have a nurse allocated to support clinical duties. Groups meet monthly for the first 6 months and 2 monthly thereafter at the clinic. ART refills, HIV clinical management and family planning are integrated into the youth club model. Youth stable on ART receive their ART refill in the group while newly initiated youth are given their ART refill by the club nurse during their clinical consultation taking place immediately after the group meeting. There is a structured interactive activity-based group session at each visit, and this provides the opportunity for development of a peer dynamic and support system.